Atta-ur-Rahman School of Applied Biosciences
Faculty Touqeer Ahmed

Touqeer Ahmed

Principal of Atta-Ur-Rahman School of Applied Biosciences
Summary

My lab is involved in investigating the molecular mechanism of memory impairment in old age neurological disorders using rodents for different behavioral studies.

Academic Background
PhD (HEALTH SCIENCES) Aga Khan University October 03, 2005 - December 12, 2009
Honours and Awards
Touqeer Ahmed Awarded gold medal for securing first division and first position. September 19, 2004
Dr.Touqeer Ahmed Research Productivity Award/2011 by Pakistan Council of Science and Technology *Category G* Research Productivity Award/ 2012 by Pakistan Council of Science and Technology *Category F* January 02, 2012
Touqeer Ahmed Best Graduate Certificate” for securing highest marks percentage ever in the history of pharmacy up to the session 2004 in the Faculty of Pharmacy, Gomal University, Dera Ismail Khan, KPK, Pakistan. September 19, 2004
Dr. Touqeer Ahmed Best Teacher Award 2017 ASAB/ NUST November 20, 2017
Publications
A NETWORK PHARMACOLOGY APPROACH VALIDATES RESVERATROL’S IN VIVO NEUROPROTECTIVE EFFECTS AGAINST NEUROTOXIC METALS-INDUCED COGNITIVE DECLINE June 25, 2026 Khyber Medical University Journal - Accepted
Betanin-encapsulated nanoparticles mitigate neurotoxicity against AlCl3-induced Alzheimer's disease via modulation of AChE/TNF-α/IL-1β expression February 19, 2026 Biochemical and Biophysical Research Communications - Volume:801, Article Number 153293
A Systematic Review of Preclinical Studies Investigating the Effects of Pharmacological Agents on Learning and Memory in Prolonged Aluminum-Exposure-Induced Neurotoxicity August 08, 2025 Brain Sciences - Volume:15, Issue:8, Article Number 849
Protective effects of resveratrol in high fat diet– and metals (Al, Pb, As)-induced metabolic and cognitive impairments May 23, 2025 Bangladesh Journal of Pharmacology - Volume:20, Issue:2, Pages 78-87
Mapping the landscape of neuroscience research trend(s) in South Asia: A bibliometric analysis of 25 years (1995–2019) May 07, 2025 Neuroscience - Volume:573, Page:9-24
Neurotoxic effects of metals on blood brain barrier impairment and possible therapeutic approaches July 17, 2024 Blood-Brain Barrier (Vitamins and Hormones Book Series) - Volume 126 , Pages 1-24
Post-exposure self-recovery reverses oxidative stress, ameliorates pathology and neurotransmitters imbalance and rescues spatial memory after time-dependent aluminum exposure in rat brain January 17, 2024 BioMetals - Pages: 20
Sex-specific effects of neuromodulatory drugs on normal and stress-induced social dominance and aggression in rats November 23, 2023 Psychopharmacology - Pages 1-14
Sexually Dimorphic Effects of Neuromodulatory Drugs on Normal and Stress-Induced Social Interaction in Rats September 27, 2023 Brain Sciences - Volume 13(10), Article Number 1378
Comparative Study of Time-Dependent Aluminum Exposure and Post-Exposure Recovery Shows Better Improvement in Synaptic Changes and Neuronal Pathology in Rat Brain After Short-Term Exposure April 24, 2023 Neurochemical Research - Pages 1-23
Influence of Sex and Muscarinic Activity on Memory Retrieval in Mouse Model of Traumatic Brain Injury January 06, 2023 Brain Sciences - Volume 13(1), Article Number 108
Neuroprotective effects of Shogaol in metals (Al, As and Pb) and high fat diet induced neuroinflammation and behavior in mice November 21, 2022 Current Molecular Pharmacology - Pages 1-17
Editorial: Synaptic Failure and Circuits' Impairment—Cognitive and Neurological Disorders—Moving a Step Forward July 13, 2022 Frontiers in Molecular Neuroscience - Volume 15, Article Number 979511
Biochemical Mechanisms of Aluminium and Other Metals Exposure, Their Brain Entry Mechanisms, Effects on Blood Brain Barrier and Important Pharmacokinetic Parameters in Neurological Disorders December 01, 2021 Book on Biochemical Mechanisms of Aluminium Induced Neurological Disorders - Chapter 1, Pages 1-32
Co-Exposure of Aluminium with other Metals Causes Neurotoxicity and Neurodegeneration December 01, 2021 Book on Biochemical Mechanisms of Aluminium Induced Neurological Disorders - Chapter 2, Pages 33-65
Gender dimorphic effect of dopamine D2 and muscarinic cholinergic receptors on memory retrieval August 01, 2021 Psychopharmacology - Volume 238, Issue 8, Pages 2225-2234
Rosmarinic acid and ursolic acid alleviate deficits in cognition, synaptic regulation and adult hippocampal neurogenesis in an Aβ1-42-induced mouse model of Alzheimer's disease March 01, 2021 Phytomedicine - Volume 83, Article Number 153490
Amyloid beta induced Neurotoxicity Impairs Cognition and Adult hippocampal Neurogenesis in a Mouse Model for Alzheimer’s disease December 24, 2020 Current Alzheimer Research - Volume 17 (11), Pages 1033-1042
Expression of DnMTs and MBDs in AlCl3-Induced Neurotoxicity Mouse Model November 11, 2020 Biological Trace Element Research - Pages 1-12
Map kinase signaling as therapeutic target for neurodegeneration October 01, 2020 Pharmacological Research - Volume 160, Article Number 105090
Anti-Oxidant Nutrients and Nutraceuticals in Aging September 29, 2020 Book on Nutrients and Nutraceuticals for Active & Healthy Ageing - Chapter 9, Pages 195-216
Age-Related Diseases September 29, 2020 Book on Nutrients and Nutraceuticals for Active & Healthy Ageing - Chapter 3, Pages 27-51
Acute effects of aerobic exercise on somatosensory evoked potentials in patients with mild cognitive impairment September 23, 2020 Brain Sciences - Volume 10(10), Article Number 663
Blood-Based Biomarkers for Predictive Diagnosis of Cognitive Impairment in a Pakistani Population July 22, 2020 Frontiers in Aging Neuroscience - Volume 12, Article Number 223
Effects of curcuminoids on cognitive deficits in young audiovisually overstimulated mice June 01, 2020 Food Bioscience - Volume 35, Article Number 100565
Muscarinic activity in hippocampus and entorhinal cortex is crucial for spatial and fear memory retrieval June 19, 2019 Pharmacological Reports - Volume 71, Issue 3, Pages 449-456
Therapeutic effects of aerobic exercise on EEG parameters and higher cognitive functions in mild cognitive impairment patients. June 03, 2019 International Journal of Neuroscience - Volume 129, Issue 6, Pages 551-562
Pharmacological Effects of Curcuminoids in Neurological Disorders April 12, 2019 Book on Curcumin for Neurological and Psychiatric Disorders: Neurochemical and Pharmacological Properties - Chapter-7, Pages 129-154
Xbox 360 Kinect Cognitive Games Improve Slowness, Complexity of EEG, and Cognitive Functions in Subjects with Mild Cognitive Impairment: A Randomized Control Trial. April 08, 2019 Games for Health Journal - Volume 8, Issue 2, Pages 144-152
Novel therapeutic strategies for stroke: The role of autophagy. April 03, 2019 Critical Reviews in Clinical Laboratory Sciences - Volume 56, Issue 3, Pages 182-199
Co-exposure of metals and high fat diet causes aging like neuropathological changes in non-aged mice brain. April 01, 2019 Brain Research Bulletin - Volume 147, Pages 148-158
Oral Exposure to Aluminum Leads to Reduced Nicotinic Acetylcholine Receptor Gene Expression, Severe Neurodegeneration and Impaired Hippocampus Dependent Learning in Mice March 20, 2019 Drug and Chemical Toxicology - -
Targeting STATs in neuroinflammation: the Road Less Traveled. March 01, 2019 Pharmacological Research - Volume 141, Pages 73-84
Regulation of autophagy by polyphenols: Paving the road for treatment of neurodegeneration. November 01, 2018 Biotechnology Advances - Volume: 36, Issue: 6, Pages: 1768-1778
Gender Dependent Contribution of Muscarinic Receptors in Memory Retrieval under Sub-Chronic Stress August 10, 2018 Neuroscience Letters - NULL
Elevated heavy metals levels in cognitively impaired patients from Pakistan. June 11, 2018 Environmental Toxicology and Pharmacology - Volume 60, Pages 100-109
Aluminum Suppresses Effect of Nicotine on Gamma Oscillations (20-40 Hz) in Mouse Hippocampal Slices June 07, 2018 CNS & Neurological Disorders-Drug Targets - Volume 17, Pages 404-411
Neuroprotective effects of Foeniculum vulgare seeds extract on lead-induced neurotoxicity in mice brain. March 26, 2018 Drug and Chemical Toxicology - Volume 41(4), Pages 399-407
Syzygium aromaticum ethanol extract reduces AlCl3-induced neurotoxicity in mice brain through regulation of amyloid precursor protein and oxidative stress gene expression February 14, 2018 Asian Pacific Journal of Tropical Medicine - Volume:11, Issue:2, Page 123-130
Protective effects of Nigella sativa L. seed extract on lead induced neurotoxicity during development and early life in mouse models January 01, 2018 Toxicology Research - Volume: 7 Issue: 1 Pages: 32-40
Cortex- and Amygdala-Dependent Learning and Nicotinic Acetylcholine Receptor Gene Expression is Severely Impaired in Mice Orally Treated with AlCl3 September 01, 2017 Biological Trace Element Research - Volume: 179, Issue: 1, Pages: 91-101
Role of cholinergic receptors in memory retrieval depends on gender and age of memory July 28, 2017 Behavioural Brain Research - Volume: 331, Pages: 233-240
Soaked Almonds Exhibit Vitamin E-dependent Memory Protective Effect in Rodent Models. June 15, 2017 International Journal of Pharmacology - Volume 13, Issue 5, Pages 448-456
Aluminum-Induced Cholinergic Deficits in Different Brain Parts and Its Implications on Sociability and Cognitive Functions in Mouse May 15, 2017 Biological Trace Element Research - Volume: 177, Issue: 1, Pages: 115-121
Resveratrol and Alzheimer's Disease: Mechanistic Insights. May 01, 2017 Molecular Neurobiology - Volume 54, Issue 4, Pages 2622-2635
Neuroprotective Effects of Citrus Fruit-Derived Flavonoids, Nobiletin and Tangeretin in Alzheimer's and Parkinson's disease. March 03, 2017 CNS & Neurological Disorders-Drug Targets - Volume 16, Issue 4, Pages 387-397
Cholinergic System and Post-translational Modifications: An Insight on the Role in Alzheimer's Disease January 15, 2017 Current Neuropharmacology - Volume 15, Issue 4, Pages 480-494
Potential Use of Curcuminoids for the Treatment of Alzheimer’s Disease January 02, 2017 Book on Neuroprotective Effects of Phytochemicals in Neurological Disorders - Chapter 24
Neuroprotective and Neurotoxic Implications of α7 Nicotinic Acetylcholine Receptor and Aβ Interaction: Therapeutic Options in Alzheimer's Disease January 01, 2017 Current Drug Targets - Volume 18, Issue 13, Pages 1537-1544
Pharmacological Effects of Turmeric on Learning, Memory and Expression of Muscarinic Receptor Genes (M1, M3 and M5) in Stress-induced Mouse Model January 01, 2017 Current Drug Targets - Volume: 18 Issue: 13 Pages: 1545-1557
Daidzein And Its Effects On Brain. January 01, 2017 Current Medicinal Chemistry - Volume 24 , Issue 4, Pages 365-375
A feedback neural circuit for calibrating aversive memory strength January 01, 2017 Nature Neuroscience - Volume: 20 Issue: 1 Pages: 90-97
Anticonvulsant, Anxiolytic, and Sedative Activities of Verbena officinalis December 21, 2016 Frontiers in Pharmacology - Volume 7, Article Number 499
Tanshinones and mental diseases: from chemistry to medicine December 01, 2016 Reviews in the Neurosciences - Volume 27, Issue 8, Pages 777-791
Quercetin and the mitochondria: A mechanistic view. October 01, 2016 Biotechnology Advances - Volume 34, Issue 5, Pages 532-549
Memory-enhancing effect of aspirin is mediated through opioid system modulation in an AlCl3-induced neurotoxicity mouse model May 01, 2016 Experimental and Therapeutic Medicine - Volume 11, Issue 5, Pages 1961-1970
Memory Enhancing Effect of Black Pepper in the AlCl3 Induced Neurotoxicity Mouse Model is Mediated Through Its Active Component Chavicine April 29, 2016 Current Pharmaceutical Biotechnology - Volume 17, Issue 11
Ginsenoside Rb1 as a neuroprotective agent: A review. April 06, 2016 Brain Research Bulletin - Volume 125, Pages 30-43
Alpha-lipoic acid-mediated activation of muscarinic receptors improves hippocampus- and amygdala-dependent memory February 18, 2016 Brain Research Bulletin - Volume 122, Pages 19-28
Ibuprofen targets neuronal pentraxins expresion and improves cognitive function in mouse model of AlCl3-induced neurotoxicity February 01, 2016 Experimental and Therapeutic Medicine - Volume 11, Issue 2, Pages 601-606
Insights Into Effects of Ellagic Acid on the Nervous System: A Mini Review January 01, 2016 Current Pharmaceutical Design - Volume 22, Issue 10, Pages 1350-1360
Cyclooxygenase I and II inhibitors distinctly enhance hippocampal- and cortex-dependent cognitive functions in mice November 01, 2015 Molecular Medicine Reports - Volume 12(5), Pages 7649-7656
Polyphenolic Composition of Crataegus monogyna Jacq.: From Chemistry to Medical Applications. September 11, 2015 Nutrients - Volume: 7 Issue: 9 Pages: 7708-7728
Pharmacological effects of Ibuprofen on learning and memory, Muscarinic receptors gene expression and APP isoforms level in Pre-frontal cortex of AlCl3-induced toxicity mouse model. April 01, 2015 International Journal of Neuroscience. - Volume 125, Issue 4, Pages 277-287
Therapetuic potential of Turmeric in Alzheimer’s disease. Curcumin or curcuminiods? April 01, 2014 Phytotherapy Research - Volume 28, Issue 4, Pages 517-525
A comparative study of curcuminoids to measure their effect on inflammatory and apoptotic gene expression in an Aβ plus ibotenic acid-infused rat model of Alzheimer's disease. July 11, 2011 Brain Research - Volume 1400, Pages 1-18
Curcuminoids Rescue Long-Term Potentiation Impaired by Amyloid Peptide in Rat Hippocampal Slices. July 01, 2011 Synapse - Volume 65, Issue 7, Pages 572-582
Curcuminoids enhance memory in an amyloid-infused rat model of Alzheimer's disease. September 01, 2010 Neuroscience - Volume 169, Issue 3, Pages 1296-1306
Inhibitory effect of curcuminoids on acetylcholinesterase activity and attenuation of scopolamine-induced amnesia may explain medicinal use of turmeric in Alzheimer's disease. February 01, 2009 Pharmacology Biochemistry and Behavior - Volume 91, Issue 4, Pages 554-559
Conferences
Identification of Hub genes in Ependymoma through Weighted Gene Co-expression Network Analysis May 23, 2025 - May 26, 2025 Iqra Arshad, Zartasha Mustansar, Touqeer Ahmed, IEEE 17th International Conference on Bioinformatics and Biomedical Technology (ICBBT 2025).
Scientist Korea institute of Science and Technology February 04, 2010 - August 22, 2011