Atta-ur-Rahman School of Applied Biosciences
Faculty Peter John

Peter John

Professor
Summary

Dr. John is Tenured Professor at Atta-Ur-Rahman School of Applied Biosciences (ASAB), NUST. Dr John has made an excellent progress in research, teaching & administration.

Academic Background
PhD (Molecular Biology/Biochemistry) Quaid-i-Azam University April 01, 2004 - February 07, 2008
Honours and Awards
Publications
Evaluation of Inhibitory mechanism of Pennisetum glaucum (Pearl Millet) Bioactive Compounds for Rheumatoid Arthritis: An In Vitro and Computational Approach February 05, 2025 Frontiers in Pharmacology - Accepted
Computational Insights into the Inhibitory Mechanism of Type 2 Diabetes Mellitus by Bioactive Components of Oryza sativa L. indica (Black rice) February 05, 2025 Frontiers in Pharmacology - Volume 15
Network medicine based approach for identifying the type 2 diabetes, osteoarthritis and triple negative breast cancer interactome: Finding the hub of hub genes February 05, 2025 Heliyon - Volume 10, Issue 17, Article Number e36650
Biocompatible gelatin-coated ferrite nanoparticles: A magnetic approach to advanced drug delivery February 05, 2025 Saudi Pharmaceutical Journal - Volume 32, Issue 6, Article Number:102066
Association analysis of Vascular Endothelial Growth Factor-A (VEGF-A) polymorphism in rheumatoid arthritis using computational approaches February 05, 2025 Scientific Reports - Volume 13, Issue 1, Article Number 21957
Dual inhibition of glycolysis and glutaminolysis for synergistic therapy of rheumatoid arthritis February 05, 2025 Arthritis Research and Therapy - Volume 25, Issue 1, Article Number 176
Molecular Link between Glo-1 Expression and Markers of Hyperglycemia and Oxidative Stress in Vascular Complications of Type 2 Diabetes Mellitus February 05, 2025 Antioxidants - Volume 12(9), Article Number 1663
Integrated bioinformatics analyses identifying potential biomarkers for type 2 diabetes mellitus and breast cancer: In SIK1-ness and health February 05, 2025 PLOS ONE - Volume 18, Issue 8, Article Number e0289839
Molecular dynamics simulations and bioinformatics’ analysis of deleterious missense single nucleotide polymorphisms in Glyoxalase-1 gene February 05, 2025 Journal of Biomolecular Structure and Dynamics - Pages 1-11
Computational analysis to investigate the anti-rheumatic potential of plant-based small molecule inhibitor targeting tumor necrosis factor α February 05, 2025 Frontiers in Pharmacology - Volume 14, Article Number 1127201
Regenerable sensor based on tris(4,7′-diphenyl-1,10-phenanthroline)ruthenium (II) for anodic and cathodic electrochemiluminescence applications February 05, 2025 Bioelectrochemistry - Volume 149, Article Number 108313
Association of Fc Gamma Receptor 3B Gene Copy Number Variation with Rheumatoid Arthritis Susceptibility February 05, 2025 Genes - Volume 13, Issue 12, Article Number 2238
Thymus serpyllum Exhibits Anti-Diabetic Potential in Streptozotocin-Induced Diabetes Mellitus Type 2 Mice: A Combined Biochemical and In Vivo Study February 05, 2025 Nutrients - Volume 14, Issue 17, Article Number 3561
Challenges and opportunities in healthcare biotechnology February 05, 2025 Book on Biotechnology in Healthcare: Applications and Initiatives - Chapter 18, Pages 321-342
Evaluation of Antidiabetic Activity of Biogenic Silver Nanoparticles Using Thymus serpyllum on Streptozotocin-Induced Diabetic BALB/c Mice February 05, 2025 Polymers - Volume 14, Issue 15, Article Number 3138
Docking and Molecular Dynamics Study to Identify Novel Phytobiologics from Dracaena trifasciata against Metabolic Reprogramming in Rheumatoid Arthritis February 05, 2025 Life - Volume 12, Issue 8, Article Number 1148
LC-MS/MS-Based Serum Protein Profiling for Identification of Candidate Biomarkers in Pakistani Rheumatoid Arthritis Patients February 05, 2025 Life - Volume 12, Issue 3, Article Number 464
Biogenic Selenium Nanoparticles: Potential Solution to Oxidative Stress Mediated Inflammation in Rheumatoid Arthritis and Associated Complications February 05, 2025 Nanomaterials - Volume 11, Article Number 2005
The prognostic outcome of ‘type 2 diabetes mellitus and breast cancer’ association pivots on hypoxia-hyperglycemia axis February 05, 2025 Cancer Cell International - Volume 21, Article Number: 351
Emerging role of selenium in treatment of rheumatoid arthritis: An insight on its antioxidant properties February 05, 2025 Journal of Trace Elements in Medicine and Biology - Volume 66, Article Number 126737
In silico analysis of non-synonymous missense SNPs (nsSNPs) in CPE, GNAS genes and experimental validation in type II diabetes mellitus through Next Generation Sequencing February 05, 2025 Genomics - Volume 113, Issue 4, Pages 2426-2440
Assessment of genetic risk of type 2 diabetes among Pakistanis based on GWAS-implicated loci February 05, 2025 Gene - Volume 783, Article Number 145563
Regulatory MicroRNAs in T2DM and Breast Cancer February 05, 2025 Processes - Volume 9(5), Article Number 819
Molecular docking and pharmacophore models to probe binding hypothesis of inhibitors of hypoxia inducible factor-1 February 05, 2025 Journal of Biomolecular Structure and Dynamics - Pages 1-12
Structural and functional annotation of PR/SET Domain (PRDM) protein family: In-silico study elaborating role of PRDM12 mutation in congenital insensitivity to pain February 05, 2025 Computational Biology and Chemistry - Volume 89, Article Number 107382
Association of VPREB1 Gene Copy Number Variation and Rheumatoid Arthritis Susceptibility February 05, 2025 Disease Markers - Volume 2020, Article ID 7189626, 5 pages
A sequencing study of CTLA4in Pakistani rheumatoid arthritis cases February 05, 2025 PLoS ONE - Volume 15(9), Article Number e0239426
Toxicological and Anti-Rheumatic Potential of Trachyspermum ammi Derived Biogenic Selenium Nanoparticles in Arthritic Balb/c Mice February 05, 2025 International Journal of Nanomedicine - Volume 15, Pages 3497-3509
Pan-transcriptomics and its applications February 05, 2025 Book on Pan-genomics: Applications, Challenges, and Future Prospects - Chapter 18, Pages 343-356
Tomorou Attenuates Progression of Rheumatoid Arthritis through Alteration in ULK-1 Independent Autophagy Pathway in Collagen Induced Arthritis Mice Model February 05, 2025 Cell Death Discovery - Volume 5, Article Number: 142, Pages 1-13
Therapeutic Potential Of Foeniculum vulgare Mill. Derived Selenium Nanoparticles In Arthritic Balb/c Mice February 05, 2025 International Journal of Nanomedicine - Volume 14, Pages 8561-8572
Nanomedicine: an emerging era of theranostics and therapeutics for rheumatoid arthritis February 05, 2025 Rheumatology - Volume 58, Issue 10, Pages 1715–1721
Exploration of shared genetic susceptibility loci between type 1 diabetes and rheumatoid arthritis in the Pakistani population February 05, 2025 BMC Research note - Volume 12, Article Number: 544
Single-Cell Omics in Autoimmune Disorders February 05, 2025 Single-Cell Omics - Chapter 9, Volume 2 (Application in Biomedicine and Agriculture) 2019, Pages 165-174
Single-Cell Omics in Metabolic Disorders February 05, 2025 Single-Cell Omics - Volume 2: Advances in Applications, Pages 153-164
Comprehensive Computational Analysis of Protein Phenotype Changes Due to Plausible Deleterious Variants of Human SPTLC1 Gene February 05, 2025 International Journal of Molecular and Cellular Medicine - Volume 8, No 1
Vitamin D as a Principal Factor in Mediating Rheumatoid Arthritis-Derived Immune Response February 05, 2025 BioMed Research International - Article Number 3494937
Identification of recombinants carrying stripe rust resistance gene Yr57 and adult plant stem rust resistance gene Sr2 through marker‐assisted selection February 05, 2025 Plant Breeding - Volume 138, Issue 2, Pages 148-153
Lack of association of –863C/A (rs1800630) polymorphism of tumor necrosis factor-a gene with rheumatoid arthritis February 05, 2025 Archives of Medical Science - Volume: 15, Issue: 2, Pages 531-536
Co-expression of HIF-1α, MDR1 and LAPTM4B in peripheral blood of solid tumors February 05, 2025 PeerJ - Volume 7, Article Number e6309
Karnal Bunt Resistance in Synthetic Hexaploid/Bread Wheat Derivatives February 05, 2025 NUST Journal of Natural Sciences - Volume 4, Issue: 1, Pages .83-99
Ethical Issues in Genomics February 05, 2025 NUST Journal of Natural Sciences - Volume 4, Issue: 1, Pages 20-29
Interlace between Chromatin Structure, DNA Repair and Ubiquitination February 05, 2025 Ubiquitination Governing DNA Repair - Implications in Health and Disease - Chapter 7
Epidemiological Investigation of Type 2 Diabetes and Alzheimer's Disease in a Pakistani Population February 05, 2025 International Journal of Environmental Research and Public Health - Volume: 15 Issue: 8 Article Number: 1582
Resistance potential of Pakistani wheat landraces (Triticum aestivum L.) against stripe rust (puccinia striformis) and karnal bunt (tilletia indica) February 05, 2025 Pakistan Journal of Botany - Volume 50(2), Pages 801-806
T cell activation Rho GTPase activating protein (TAGAP) is upregulated in clinical and experimental arthritis February 05, 2025 Cytokine - Volume 104, Pages 130-135
Therapeutic Potential of Selenium Nanoparticles February 05, 2025 Journal of Nanomedicine and Nanotechnology - Volume 9, Issue 1, 1000487, online published on 21 Feb 2018
Immunomodulatory and therapeutic role of Cinnamomum verum extracts in collagen-induced arthritic BALB/c mice February 05, 2025 Inflammopharmacology - Volume 26(1), Pages 157-170
Identification and in silico analysis of functional SNPs of human TAGAP protein: A comprehensive study February 05, 2025 PLoS ONE - Volume: 13, Issue: 1, Article Number: e0188143
Reverse Engineering and Its Applications February 05, 2025 Omics Technologies and Bio-engineering : Towards Improving Quality of Life - Volume 1, Chapter 5, Pages 95-110
Case-control study of vitamin D receptor gene polymorphism in Pakistani rheumatoid arthritis patients February 05, 2025 Revista Brasileira de Reumatologia (English Edition) - Volume 57, Issue 6, Pages 633-636
Association of rs182429 variant in TAGAP with rheumatoid arthritis in Pakistani population February 05, 2025 Meta Gene - Volume 14, Pages 59-63
In-Silico characterization of SCN9A: A protein that mediates voltage-dependent sodium ion permeability of excitable membranes February 05, 2025 International Journal of Biosciences - Vol. 11, No. 5, Pages 378-385
Progression pattern of rheumatoid arthritis: A study of 500 Pakistani patients February 05, 2025 Pakistan Journal of Pharmaceutical Sciences - Vol. 30, Issue 4, Pages 1219-1223
The Mantle of Advanced Glycation end Products in Micro-and Macrovascular Complications of Type 2 Diabetes Mellitus February 05, 2025 Current Research in Diabetes and Obesity Journal - Volume 2, Issue 5, Article Number 555596
Assessment of Pakistani and Iranian Bread Wheat Landraces using Multivariate Analysis for Grain Yield February 05, 2025 Pakistan Journal of Botany - Volume: 49 Issue: 6 Pages: 2451-2458
Mapping Autosomal Recessive Intellectual Disability: Combined Microarray and Exome Sequencing Identifies 26 Novel Candidate Genes in 192 Consanguineous Families February 05, 2025 Molecular Psychiatry - Vol. 23(4), Pages 973-984
Exome sequencing revealed a novel splice site variant in the ALX1 gene underlying frontonasal dysplasia February 05, 2025 Clinical Genetics - Volume 91, Issue 3, Pages 494-498
A replication study of 49 Type 2 diabetes risk variants in a Punjabi Pakistani population February 05, 2025 Diabetic Medicine - Volume 33, Issue 8, Pages 1112-1117
Polymorphisms in DNA repair genes XRCC1 and OGG1 lead to the progression of rheumatoid arthritis in Pakistani patients February 05, 2025 Pakistan Journal of Pharmaceutical Sciences - Volume 29, No.4, Pages 1189-1195
The microRNA regulatory network: a far-reaching approach to the regulate the Wnt signaling pathway in number of diseases February 05, 2025 Journal of Receptors and Signal Transduction - Volume 36(3), Pages 310-318
Prevalence of type 2 diabetes-associated complications in Pakistan February 05, 2025 International Journal of Diabetes in Developing Countries - Volume 36, Issue 2, Pages 179-188
Association of Non-Genetic Risk Factors with Coronary Artery Disease in Pakistani Population February 05, 2025 Annals of PIMS - Volume 12(2), Pages 98-102
Homozygous mutations in NTRK1 gene underlie congenital insensitivity to pain with anhidrosis in Pakistani families February 05, 2025 Neurology Asia - Volume 21(2), Pages 129-136
Lack of tumor necrosis factor alpha gene polymorphism -857c/t (rs1799724) association in Pakistani rheumatoid arthritis patients February 05, 2025 International Journal of Rheumatic Diseases - 4 pages
Identification of a homozygous missense mutation in LRP2 and a hemizygous missense mutation in TSPYL2 in a family with mild intellectual disability February 05, 2025 Psychiatric Genetics - Volume 26(2), Pages 66-73
Electrochemiluminescence of Luminol-Tripropylamine System February 05, 2025 Electrochimica Acta - Volume 196, Pages 245-251
Rheumatoid arthritis: What have we learned about the causing factors? February 05, 2025 Pakistan Journal of Pharmaceutical Sciences - Volume 29, No.2, Pages 629-645
Chemiluminescence of creatinine/H2O2/Co(2+) and its application for selective creatinine detection February 05, 2025 Biosensors and Bioelectronics - Volume 75, Pages 347-351
RANKL Signating Pathway: A potential Target for Antiresorptive Therapy in Rheumatoid Arthritis February 05, 2025 NUST Journal of Natural Sciences - Volume 3, No. 1, Pages 35-52
Pharmacogenomics of Type 2 Diabetes Mellitus: A Step Toward Personalized Medicine February 05, 2025 NUST Journal of Natural Sciences - Volume 3, No. 1, Pages 19-26
Signating Pathways Involved in Rheumatoid Arthritis: Targets for New Therapeutic Interventions February 05, 2025 NUST Journal of Natural Sciences - Volume 3, No. 1, Pages 53-64
Data interpretation: deciphering the biological function of Type 2 diabetes associated risk loci February 05, 2025 Acta Diabetologica - Volume 52, Pages789-800
Feeding of organic plant extracts to animals during vivisection, extract dosage feeding formula (exdff): a novel technique February 05, 2025 Basic Research Journal of Agricultural Science and Review - Volume 4(6), Pages 172-175
Mutations in DCPS and EDC3 in autosomal recessive intellectual disability indicate a crucial role for mRNA decapping in neurodevelopment February 05, 2025 Human Molecular Genetics - Volume 24(11), Pages 3172-3180
Genetic link of type 1 diabetes susceptibility loci with rheumatoid arthritis in Pakistani patients February 05, 2025 Immunogenetics - Volume 67, Issue 5-6, Pages 277-282
Association of 32 type 1 diabetes risk loci in Pakistani patients February 05, 2025 Diabetes Research and Clinical Practice - Volume 108, Issue 1, Pages 137-142
Homozygosity mapping of autosomal recessive intellectual disability loci in 11 consanguineous Pakistani families February 05, 2025 Acta Neuropsychiatrica - Volume 27, Issue 1, Pages 38-47
Conferences
Association of TCF7L2 Genetic Polymorphism with Type 2 Diabetes in Pakistani Patients February 17, 2023 - February 18, 2023 Prof Attya Bhatti, Prof Peter John, Hadiqa Mubashir, EUROASIA Congress on Scientific Researches and Recent Trends-X
Pro-Inflammatory, Anti-Oxidative, Therapeutic Potential of Moringa Oleifera in Rheumatoid Arthritis February 16, 2023 - February 17, 2023 Peter John, Attya Bhatti, Safa Bajwa, Euroasia International Congress on Scientific Research and Recent Trends-X
Data Integration for Big Data analytics to identify the gaps in Rheumatoid Arthritis Genomics in a Post-GWAS era April 28, 2022 - April 29, 2022 Prof. Dr Attya Bhatti, Sidrah Jahangir, Peter John, Muhammad Muaaz Aslam, 2022 2nd International Conference on Advance Computing and Innovative Technologies in Engineering, ICACITE 2022
Therapeutic Potential of Thymus serpyllum in Collagen Induced Arthritic Mice July 05, 2021 - July 06, 2021 Peter John, Arooma Janat, Attya Bhatti, 4th HEALTH SCIENCES AND INNOVATION CONGRESS