Atta-ur-Rahman School of Applied Biosciences
Faculty Naila Naz

Naila Naz

HoD Research
Summary

A distinguished academic and researcher specializing in Gastroenterology, Endocrinology, and Neurosciences whose research focuses on reproduction, paternal, maternal, and child health, neurodevelopmental, neurodegenerative, and metabolic disorders.

Academic Background
PhD (Gastroenterology and Endocrinology) Georg-August Universität Göttingen September 01, 2004 - August 30, 2009
Honours and Awards
Publications
Valproic acid-induced placental toxicity: mechanistic insights and the therapeutic potential of bioactive folates November 18, 2025 Naunyn-Schmiedeberg's Archives of Pharmacology - Pages 1-12
A paternal methylation error in the congenital hydrocephalic Texas (H-Tx) rat is partially rescued with natural folate supplements. January 13, 2023 International Journal of Molecular Sciences - Volume 24(2), Article Number 1638
Cerebral Folate Metabolism in Post-Mortem Alzheimer’s Disease Tissues: A Small Cohort Study December 30, 2022 International Journal of Molecular Sciences - Volume 24(1), Article Number 660
Folate Related Pathway Gene Analysis Reveals a Novel Metabolic Variant Associated with Alzheimer’s Disease with a Change in Metabolic Profile May 24, 2022 Metabolites - Volume:12, Issue:6, Article Number 475
A Decade of Mighty Lipophagy: What We Know and What Facts We Need to Know? November 05, 2021 Oxidative Medicine Cellular Longevity - Volume 2021, Article ID 5539161, 18 pages
Subarachnoid cerebrospinal fluid is essential for normal development of the cerebral cortex June 01, 2020 Seminars in Cell and Developmental Biology - Volume 102, Pages 28-39
Altered folate binding protein expression and folate delivery are associated with congenital hydrocephalus in the hydrocephalic Texas rat January 01, 2019 Journal of Cerebral Blood Flow and Metabolism - Volume 39, Issue 10, Pages 2061-2073
Gene and Cell Therapy for Muscular Dystrophies: Are We Getting There? October 12, 2018 Human Gene Therapy - Volume 29(10), Pages 1098-1105
Mediators of hypoxia in a rat model of sterile-induced acute liver injury December 01, 2017 International Journal of Clinical and Experimental Pathology - Volume 10(12), Pages 11471-11479
Reabsorption of iron into acutely damaged rat liver: A role for ferritins November 07, 2017 World Journal of Gastroenterology - Volume:23, Issue:41, Pages:7347-7358
Neonatal hydrocephalus is a result of a block in folate handling and metabolism involving 10-formyltetrahydrofolate dehydrogenase August 01, 2016 Journal of Neurochemistry - Volume 138, Issue 4, Pages 610-623
Regulation of iron uptake in primary culture rat hepatocytes: the role of acute-phase cytokines April 01, 2014 Shock - Volume 41(4), Pages 337-345
Differential gene expression of chemokines in KRAS and BRAF mutated colorectal cell lines: role of cytokines March 21, 2014 World Journal of Gastroenterology - Volume 20(11), Pages 2979-2994
Differential regulation of ferritin subunits and iron transport proteins: An effect of targeted hepatic X-irradiation December 12, 2013 BioMed Research International - Volume 2013, Article ID 353106, 8 pages
Rat model of fractionated (2 Gy/day) 60 Gy irradiation of the liver: long-term effects August 01, 2013 Radiation and Environmental Biophysics - Volume 52, Pages 321-338
Ferritin L is the sole serum ferritin constituent and a positive hepatic acute-phase protein. June 01, 2013 Shock - Volume:39, Issue:6, Pages 520-526
Ferritin L and ferritin H are differentially located within hepatic and extra hepatic organs under physiological and acute phase conditions April 01, 2013 International Journal of Clinical and Experimental Pathology - Volume 6(4), Pages 622–629
Ferroportin-1 is a 'nuclear'-negative acute-phase protein in rat liver: a comparison with other iron-transport proteins June 01, 2012 Laboratory Investigation - Volume 92, Pages 842-856
Immunodetection of cyclooxygenase-2 (COX-2) is restricted to tissue macrophages in normal rat liver and to recruited mononuclear phagocytes in liver injury and cholangiocarcinoma February 01, 2012 Histochemistry and Cell Biology - Volume:137, Issue:2, Page:217-233
Comparison of changes in gene expression of transferrin receptor-1 and other iron-regulatory proteins in rat liver and brain during acute-phase response May 01, 2011 Cell and Tissue Research - Volume: 344, Pages:299-312
Myeloperoxidase and elastase are only expressed by neutrophils in normal and in inflammed liver March 01, 2011 Histochemistry and Cell Biology - Volume:135, Issue:3, Pages 305-315
Changes in gene expression of DOR and other thyroid hormone receptors in rat liver during acute-phase response November 01, 2010 Cell and Tissue Research - Volume:342, Issue:2, Pages 261-272
Single-dose gamma-irradiation induces up-regulation of chemokine gene expression and recruitment of granulocytes into the portal area but not into other regions of rat hepatic tissue April 01, 2010 American Journal of Pathology - Volume:176, Issue:4, Pages 1801-1815
Conferences
research fellow University of Manchester January 01, 2021 - January 13, 2023
senior post doc University of Manchester November 30, 2018 - December 31, 2020
Higher Education Fellow University of Manchester January 15, 2014 - December 29, 2023
post doctoral research asscociate University of Manchester January 06, 2014 - December 01, 2018
POst doctoral Research associate University of Goettingen September 01, 2011 - December 31, 2013
PHD Student University of Goettingen September 01, 2009 - September 01, 2011
Research Assistant University of Goettingen September 30, 2008 - September 01, 2009