Summary
Tenured Professor
Academic Background
PhD
(Cancer Genetics) Quaid-i-Azam University
September 21, 2010 - March 21, 2015
Honours and Awards
FICS-2017
FICS-2017 best project award in Biotechnology for nano-medicine designed to treat HIV
September 20, 2017
Best Teacher Award 2020
Best teacher award for year 2019-2020 , ASAB,, NUST
December 14, 2020
School/College Best Researcher Awards-2021
December 26, 2022
Publications
Proteomics, metabolomics, and precision medicine
January 01, 2026
Nanotheranostics and Precision Oncology - Chapter 8, Pages 185-213
Oncogenesis: Genetic basis
January 01, 2026
Nanotheranostics and Precision Oncology - Chapter 1, Pages 3-27
Drug resistance in cancer
January 01, 2026
Nanotheranostics and Precision Oncology - Chapter 5, Pages 111-136
Hallmarks of cancer
January 01, 2026
Nanotheranostics and Precision Oncology - Chapter 2, Pages 29-56
Investigating the pathogenic potential of PKC-eta UTR variants in cancer progression
December 01, 2025
Computers in Biology and Medicine - Volume:199, Article Number 111283
Comprehensive analysis of gene expression alterations in breast cancer patients via PKCθ-TBK1-mTORC1 signaling pathway
November 28, 2025
BMC Cancer - Volume 25, Article Number 1844
Role of PRKCZ non-synonymous genetic variants in breast cancer development
November 06, 2025
Cancer Cell International - Volume 25, Article Number: 390
Comprehensive computational analysis of PKCδ non-synonymous variants identifies rs1703863535 as a potential breast cancer biomarker
October 29, 2025
BMC Cancer - Volume:25, Issue:1, Article Number 1667
Computational insights into PKCθ non-synonymous SNPs: from structural changes to functional implications
August 23, 2025
Journal of Biomolecular Structure and Dynamics - Pages 1-21
Inherited metabolic disorders: presentation, clinical types, laboratory diagnosis and genetic markers
August 11, 2025
Orphanet Journal of Rare Diseases - Volume:20, Issue:1, Article Number: 422
Missense variants in PRKCD: elucidating their potential association with breast cancer
July 28, 2025
Breast Cancer Research - Volume 27, Article Number: 139
Association of PRKCQ variants with breast cancer susceptibility and clinicopathological features
July 01, 2025
BMC Cancer - Volume:25, Issue:1, Article Number 1069
Zapotin mitigates breast cancer progression by targeting PKCε mediated glycolytic pathway regulation
April 28, 2025
BMC Cancer - Volume:25, Issue:1, Article Number 798
Unravelling the role of PRKCI and key-cancer related genes in breast cancer development and metastasis
March 18, 2025
Discover Oncology - Volume 16, Article Number 350
HCV and HBV Genotypes: Vital in the Progression of HCV/ HBV Co-Infection
January 08, 2025
BMC Gastroenterology - Volume: 25, Article Number: 6, Pages:09
Investigating the role of non-synonymous variant D67N of ADGRE2 in chronic myeloid leukemia
November 05, 2024
BMC Cancer - Volume 24, Article Number: 1354
Genetic Variants at PRKCG Splice and UTR Sites Promote Cancer Susceptibility by Disrupting Epigenetic and miRNA Regulatory Network
October 28, 2024
Journal of Cancer - Vol: 15, Issue: 20, Paegs: 6644-6657
Pathogenic nsSNPs of protein kinase C-eta with hepatocellular carcinoma susceptibility
October 19, 2024
Cancer Cell International - Volume 24, Article Number: 346
Genetic polymorphism in untranslated regions of PRKCZ influences mRNA structure, stability and binding sites
September 13, 2024
BMC Cancer - Volume 24(1), Article Number: 1147
Possible prognostic impact of PKCι genetic variants in prostate cancer
January 10, 2024
Cancer Cell International - Volume 24, Article Number 24
Cross talk of tumor protein D52 (TPD52) with KLF9, PKCε, and MicroRNA 223 in ovarian cancer
October 13, 2023
Journal of Ovarian Research - Volume 16, Issue 1, Article Number: 202
Impact of IL-12B Genetic Variants on Antiviral Treatment Response among Hepatitis B Patients in Pakistan
September 12, 2023
Livers - Volume 3, Issue 3, Pages 494-506
Exploring the prognostic significance of PKCε variants in cervical cancer
September 04, 2023
BMC Cancer - Volume 23, Issue 1, Article Number 819
Investigating pathogenic SNP of PKCι in HCV-induced hepatocellular carcinoma
August 02, 2023
Scientific Reports - Volume 13, Article Number 12504
Non-synonymous SNPs variants of PRKCG and its association with oncogenes predispose to hepatocellular carcinoma
June 21, 2023
Cancer Cell International - Volume 23, Article Number: 123
Expression Profiles of Hepatic Immune Response Genes in HEV Infection
March 01, 2023
Pathogens - Volume 12(3), Article Number 392
Mutation pattern of cancer suppressor p53 gene in factory workers exposed to polypropylene and impact on their reproductive hormones
February 14, 2023
Journal of Gene Medicine - Pages 1-10, Article Number e3483
Elucidating the role of missense SNP of protein kinase C epsilon in HCV-induced hepatocellular carcinoma
February 13, 2023
BMC Cancer - Volume 23, Article Number 147
Investigation of UTR Variants by Computational Approaches Reveal Their Functional Significance in PRKCI Gene Regulation
January 18, 2023
Genes - Volume 14, Issue 2, Article Number 247
Pathogenicity of PKCγ Genetic Variants—Possible Function as a Non-Invasive Diagnostic Biomarker in Ovarian Cancer
January 16, 2023
Genes - Volume 14, Issue 1, Article Number 236
Bioassay-guided isolation and characterization of lead antimicrobial compounds from Acacia hydaspica plant extract
December 15, 2022
AMB Express - Volume 12, Issue 1, Article Number: 156
Analyzing PKC Gamma (+19,506 A/G) polymorphism as a promising genetic marker for HCV-induced hepatocellular carcinoma
November 30, 2022
Biomarker Research - Springer Nature
Investigating Isoform Switching in RHBDF2 for its role in Human Neoplastic Growth in Breast Cancer
November 25, 2022
PeerJ - Volume 10, Article Number e14124
PRKCE non-coding variants influence on transcription as well as translation of its gene
October 26, 2022
RNA Biology - Volume 19, Issue 1, Pages 1115-1129
Prevention of Testicular Damage by Indole Derivative MMINA via Upregulated StAR and CatSper Channels with Coincident Suppression of Oxidative Stress and Inflammation: In Silico and In Vivo Validation
October 19, 2022
Antioxidants - Volume 11(10), Article Number 2063
Manipulation of Interleukin-6 (IL-6) and Transforming Growth Factor Beta-1(TGFβ-1) towards viral induced liver cancer pathogenesis
October 10, 2022
PLoS One - Volume 17(10), Article Number e0275834
Single Cell Omics
October 03, 2022
Book on Omics Technologies for Clinical Diagnosis and Gene Therapy: Medical Applications in Human Genetics - Chapter 10, Pages 156-173
Sulindac acetohydrazide derivative attenuates against cisplatin induced organ damage by modulation of antioxidant and inflammatory signaling pathways
July 11, 2022
Scientific Reports - Volume 12, Issue 1, Article Number 11749
Influence of PRKCE non-synonymous variants on protein dynamics and functionality
July 01, 2022
Human Molecular Genetics - Volume 31, Issue 13, Pages 2236-2261
PLK4 is upregulated in prostate cancer and its inhibition reduces centrosome amplification and causes senescence
June 15, 2022
Prostate - Pages 1-13
Determining KLF14 tertiary structure and diagnostic significance in brain cancer progression
May 16, 2022
Scientific Reports - Volume 12, Article Number 8039
Association of CTLA-4 and IL-4 polymorphisms in viral induced liver cancer
May 07, 2022
BMC Cancer - Volume 22, Issue 1, Article Number 518
Impact of deleterious missense PRKCI variants on structural and functional dynamics of protein
March 08, 2022
Scientific Reports - Volume 12, Issue 1, Article Number 3781
Predicting 3D Structure, Cross Talks, and Prognostic Significance of KLF9 in Cervical Cancer
January 03, 2022
Frontiers in Oncology - Volume 11, Article Number 797007
Acacia hydaspica R. Parker ethyl-acetate extract abrogates cisplatin-induced nephrotoxicity by targeting ROS and inflammatory cytokines
August 26, 2021
Scientific Reports - Volume 11(1), Article Number 17248
Tissue microarray profiling and integrative proteomics indicate the modulatory potential of Maytenus royleanus in inhibition of overexpressed TPD52 in prostate cancers
June 07, 2021
Scientific Reports - Volume 11, Article Number 11935
Evaluation of pro-apoptotic potential of taxifolin against liver cancer
May 25, 2021
PeerJ - Volume 9, Article Number e11276
Molecular docking, pharmacokinetic studies, and in vivo pharmacological study of indole derivative 2-(5-methoxy-2-methyl-1H-indole-3-yl)-N'-[(E)-(3-nitrophenyl) methylidene] acetohydrazide as a promising chemoprotective agent against cisplatin induced organ damage
March 18, 2021
Scientific Reports - Volume 11(1), Article Number 6245
Genetic markers of osteoarthritis: early diagnosis in susceptible Pakistani population
February 09, 2021
Journal of Orthopaedic Surgery and Research - Volume 16, Article Number 124
Unravelling Structure, Localization, and Genetic Crosstalk of KLF3 in Human Breast Cancer
December 28, 2020
BioMed Research International - Volume 2020, Article ID 1354381, 15 pages
Molecular Docking Using Chimera and Autodock Vina Software for Nonbioinformaticians
June 19, 2020
JMIR Bioinformatics and Biotechnology - Volume 1(1), Article Number e14232
Adapting the Foreign Soil: Factors Promoting Tumor Metastasis
March 21, 2020
Book on Essentials of Cancer Genomic, Computational Approaches and Precision Medicine - Chapter 8, Pages 171-196
Phytochemical analysis and Evaluation of hepatoprotective effect of Maytenus royleanus leaves extract against anti-tuberculosis drug induced liver injury in mice
March 16, 2020
Lipids in Health and Disease - Volume 19(1), Article Number: 46
Evaluating the protective potency of Acacia hydaspica R. Parker on histological and biochemical changes induced by Cisplatin in the cardiac tissue of rats.
July 23, 2019
BMC Complementary and Alternative Medicine - Volume 19, Article Number 182
Silver nanoparticles of Aloe vera gel as strong therapeutic candidates
July 18, 2019
International Journal of Biosciences - Volume 15, Issue No. 1, pages 360-373
Expression of suppressor of cytokine signaling 3 (SOCS3) and interleukin-6 (-174-G/C) polymorphism in atopic conditions
June 28, 2019
PLoS ONE - Volume 14, Issue 6, Article Number e0219084
Centriole Overduplication is the Predominant Mechanism Leading to Centrosome Amplification in Melanoma
March 01, 2018
Molecular Cancer Research - NULL
Antioxidant activity of polyphenolic compounds isolated from ethyl-acetate fraction of Acacia hydaspica R. Parker
January 25, 2018
Chemistry Central Journal - NULL
Evaluation of antioxidant, anti-hemolytic and anticancer activity of various solvent extracts of Acacia hydaspica R. Parker aerial parts
July 29, 2016
BMC Complementary and Alternative Medicine - Volume: 16, Article Number: 258
MicroRNAs in skin response to UV radiation.
September 01, 2013
Current Drug Targets - Volume 14, Issue 10, Pages 1128-1134
Assessment of phytochemicals, antioxidant, anti-lipid peroxidation and anti-hemolytic activity of extract and various fractions of Maytenus royleanus leaves.
July 22, 2013
BMC Complementary and Alternative Medicine - Volume 13, Article Number 143
Evaluation of diverse antioxidant activities of Galium aparine.
February 01, 2013
Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy - Volume 102, Pages 24-29
Antioxidant activity, total phenolic and total flavonoid contents of whole plant extracts Torilis leptophylla L.
November 16, 2012
BMC Complementary and Alternative Medicine - Volume 12, Article Number 221
Protective effects of Launaea procumbens against KBrO3-induced hepatic serum marker enzymes."
December 22, 2011
African Journal of Pharmacy and Pharmacology - Volume 5, Issue 23, Pages 2639-2641
Conferences
Research Fellow/ Post Doctorat
University of Wisconsin, Madis
October 01, 2015 - July 27, 2016